natinuel cataloge

Medical products falling within Class III, intended for correcting congenital and acquired soft tissue deficits. Available in monophase sterile hydrogel form, intended for injection, non-pyrogenic, consisting of sodium hyaluronate cross-linked via the 1,4-butanediol-diglycidylether (BDDE) cross-linking agent, containing two amino acids (glycine and L-proline), buffered with non-pyrogenic water. The products have a pH of 6.5 ± 1, they have very good mechanical properties such as viscosity and fl exibility and high compression strength and cohesion in the presence of water.

Sodium hyaluronate, used in Alium h24 and Alium h28, is raw material purifi ed by bacterial fermentation (biotechnological method) using Streptococcus Equi. It is a naturally occurring strain of bacteria, not a genetically modifi ed organism. This strain of bacteria ensures highest purity and safety as it does not produce streptokinase, hyaluroni- dase, erythrogenic toxins, hemolysin, endotoxin or any other toxins or immunogenic contaminants.

The product with a concentration of 24 mg/ml of hyaluronic acid is injected into the middle dermis and it is perfect for the correction of nasolabial folds, surface wrin- kles, lacrimal grooves and the wrinkles in the under-eye area. The product is perfect for increasing lip volume and shaping the area of the mouth.

• average concentration of hyaluronicacid, high fl exibility
• natural effect and increased patient comfort
• high standard of safety
• slow biodegradation and long-lasting effect

Medical products falling within Class III, intended for cor- recting congenital and acquired soft tissue defi cits. Ava- ilable in mono-phase sterile hydrogel form, intended for injection, non-pyrogenic, consisting of sodium hyaluro- nate cross-linked via the 1,4-butanediol-diglycidylether (BDDE) cross-linking agent, containing two amino acids (glycine and L-proline), buffered with non-pyroge- nic water. The products have a pH of 6.5 ± 1, they have very good mechanical properties such as viscosity and fl exibility and high compression strength and cohesion in the presence of water.

Sodium hyaluronate, used in Alium h24 and Alium h28, is raw material purifi ed by bacterial fermentation (biotech- nological method) using Streptococcus Equi. It is a naturally occurring strain of bacteria, not a genetically modifi ed organism. This strain of bacteria ensures highest purity and safety as it does not produce streptokinase, hyaluroni- dase, erythrogenic toxins, hemolysin, endotoxin or any other toxins or immunogenic contaminants.

The product with a concentration of 28 mg/ml of hyalu- ronic acid is injected into the deep dermis and it is per- fect for the correction of deep wrinkles, shaping the area of zygomatic bones, the cheeks, jawline, chin creases and for nose correction. The product is perfect for im- proving face contour.

• high concentration of hyaluronic acid, high fl exibility
• optimum rheological properties ensuring natural effect
• high standard of safety
• slow biodegradation and long-lasting effect

BIO ENZY: Is an innovative complex product that combines different substances capable of exerting rapid keratolytic action causing no reddening or burning sensation. The product is indicated for the treatment of hyperkeratosis in every part of the body, it can also be combined with different types of anti-aging treatment. It is also be successfully used to treat hyperpigmented skin.

• Rapid elimination of the excessive stratum corneum thickening.
• It gives an immediate softness and smoothness sensation in skin surface.

KERATINASE: Natural exfoliating enzyme offering keratolytic action. It rapidly eliminates dead cells of the stratum corneum.

UREA: Substance which has dual action (depending on its concentration), increases skin hydration and softens it dissolving keratin (a filamentous protein produced by keratinocytes) which is the main constituent of the cells of the stratum corneum. This helps to eliminate the excessive stratum corneum thickening and, at the same time, to maintain proper hydration of the skin.

PEELMOIST: An innovative complex product capable of degrading the corneodesmosomes, exfoliating the corneocytes on the surface of the skin. At the same time, thanks to a special molecular film, the product reduces roughness and dryness of the skin exfoliating dead skin cells. It hydrates the skin naturally.

Is the ideal product to regenerate and bio-stimulate tissue in the eye area. Two PHAs gluconolactone and lactobionic acid are associated with particular AHAs, the malic acid and lipoic acid to support a restructuring and rejuvenation of both epidermal and dermal. In addition, substances of natural extraction and hyaluronic acid facilitate the recovery of surface hydration.

Revitalizes the metabolic mechanisms regeneration, improves cell turnover, improves cell cohesion and hydration, instantly gives smoothness and softness to the touch, bio-protective and antioxidant action, anti-wrinkle smoothing action.

PHAs: Substances with multiple properties capable of acting on the bond strength of corneo- desmosomes preserving and restoring proper cellular metabolism of the corneocytes (Stratum Corneum). It has strong moisturizing properties, counteracts oxygen free radicals, improves the barrier function, especially in sensitive skin and improves skin texture.

MALIC ACID: Enhances the biological mechanisms, optimizes energy production in cells.

LIPOIC ACID: A powerful antioxidant and hydroxyl free radical scavenger. Lipoic acid is capable of preventing the ascorbic acid oxidation and of inhibiting lipid peroxidation catalyzed by copper. It’s water and fat soluble which makes it possible to reach into different layers of skin cells.

HYALURONIC ACID: It has strong rehydrating properties which make the Stratum Corneum soft and flexible, it helps reinforce the skin barrier enabling it to combat harsh external aggressions, it improves cell cohesion and promotes the regenerative mechanisms of the epidermis.

CHAMOMILE: Has soothing emollient purifying properties.

Stimulating, smoothing cream indicated for the the first signs of aging treatment. It can revitalize metabolic processes affecting both the dermis to the epidermis in the skin All this will produce a clear overall improvement of the entire skin structure.

Improves the skin tone and elasticity, the skin becomes smoother, firmer and more silky. It improves and preserves the hydration, has anti-wrinkle properties, makes the color more uniform and bright, increases skin resistance to external aggressions.

MANDELIC ACID: This AHAs help to remodel epidermis cellular turnover, enhances the proliferation and differentiation of keratinocytes, it has also an sanitizing, moisturizing and firming activity. Gives immediate radiance to the skin even skin tone complexion.

DECAPEPTIDE-3: Reduces and prevents fine lines and wrinkles in an active way through a bio-stimulation of new cells. It has action of general skin rejuvenation, improving the anabolic mechanisms. strengthen the elasticity and skin tone, by improving the neo-synthesis of collagen elastin, fibronectin and laminin.

DIPEPTIDE-4: Bio-protector broad range, protects the skin from oxidative stress, improves the natural defense mechanisms against oxidative stress (SOD and catalase), reduces carbonylation protein, improves the protection of the DNA, decreased lipid peroxidation, it protects against damage glycation.

SERICIN: Promotes the biological mechanisms of skin reconstruction and regeneration, improves hydration and regulates excessive evaporation of water (TEWL), increases resistance against external agents and strengthens the skin barrier. It has film-forming properties and anti- elastase activity.

SHEA BUTTER: It has a high content of unsaponifiables (from 12% to 18%), and basic substances essential for the improvement of skin tone, and in particular for the maintenance of its natural elasticity.

SOLAR FILTERS: Medium protection against UVA-UVB.

Is the modern scientific answer to the desire to have a skin with ayounger biological age. Its special formula has been developed to give the product a high activity dermatology. Bio-Derm, was designed to create biochemical synergy. It can promote regeneration and restructuring to more levels in the skin tissue. Prerogative basic to a marked rejuvenation, bio- functional with improvement of wrinkles, tone and skin elasticity.

Active collagen, elastin GAGs and proteoglycans, production. It improves cell turnover in the epidermis and the mechanisms that regulate energy metabolism. Bio-Derm also protects cellular structures from free radicals attack, counteracts proteins glycation and preserves optimum hydration.

AHAs (Amphoteric System): They implement an improvement of epidermal cell turnover, hydration, ECM components (collagen,elastin GAGs etc.) synthesis, and reducing lines and wrinkles. The amphoteric system through a controlled release of alpha-hydroxy acids allows the use of high concentrations of these substances also on sensitive skin significantly reducing the sensation of tingling or burning.

MANDELIC ACID: Epidermal re-modulator cell, sanitizing, compacting and gives Immediate radiance of the skin.

PEPTIDE: Particular peptide, increases the collagen, elastin, proteoglycans and GAGs, biosynthesis, improves the mechanisms of self-repair of the skin, contrary to the process of Glycation, regulates MMPs, increases the endogenous antioxidant system and improves neo- angiogenesis. It counteracts skin inflammation (by blocking interleukin-1).

SOLAR FILTERS: Medium protection against UVA-UVB.

SERICIN: Promotes the biological mechanisms of reconstruction and regeneration of skin tissue, improves hydration and regulates excessive evaporation of water (TEWL), increases the resistance against external agents and reinforces the skin barrier. Film-forming properties and has an anti-elastase activity.

Is a new generation highly active bioceutical preparation with bio-stimulating and restorative properties. The cream contains high quality biologically active substances. These substances act in different ways but synergically with one anothet to revitalize cell metabolism, catabolic and anabolic mechanisms are rebalanced creating ideal conditions for a strong biochemical action of a radical structural rejuvenation, combined with functional and aesthetic rejuvenation of different layers of skin tissue.

The skin becomes smoother, more relaxed and brightened, it Increasse cell cohesion Stimulates metabolic mechanisms, tones the facemuscles, increases elasticity and skin firmness, evens out the basic skin color, strong anti-wrinkle action, the skin becomes more resistant and protected, preserves optimal hydration.

AHAs-AKA (Acid- Glycolic, Pyruvic, Malic, Lactic): Reduces thickening of the stratum corneum, increases internal epidermis thickness, reactivates cellular metabolism contributes to the renewal of the dermis, has a positive effect on many biochemical skin processes.

MATRIXYL-6 Lipopeptide: It smooths the skin texture and fills wrinkles in rebuilding the skinwhere it is needed. It effects similar to Matrikine that stimulates the synthesis of six major components of the Matrix Dermal and GDE (Junction Dermo-epidermis (collagen I, III, IV, fibronectin, hyaluronic acid and laminin-5).

UREA: It ‘the carbamic acid amide, has strong moisturizing and emollient. Urea is naturally present on healthy skin, is a component of the natural moisturizing factor (NMF) of the epidermis. Urea promotes skin regeneration and restores the skin barrier. It improves the penetration of active layers in the sub-cutaneous.

SERICIN: Promotes the biological mechanisms of reconstruction and regeneration of skin tissue, improves hydration and regulates excessive evaporation of water (TEWL), increases the resistance against external agents and reinforces the skin barrier. Has film-forming and anti- elastase properties.

SOLAR FILTERS: Medium protection against UVA-UVB.

Bioceutic multiple action, its unique formulation incorporates the synergy of various active substances with strong bio-stimulating and invigorating properties and energizing the anabolic mechanisms responsible for the production of collagen, elastin and GAGs. Other substances present in the formulation ensure excellent protection against free radicals and stimulate regenerative processes.

The skin is smoother, it improves brightness and hydration, it improves skin elasticity and skin tone, progressive reduction of fine lines and wrinkles, promotes revitalization of metabolic processes, antioxidant broad spectrum.

AHAs (Glycolic Acid, Mandelic Acid): Reduces thickening of the stratum corneum by having an impact on the bonds between the corneocytes, increases the internal thickness of the epidermis, reactivates cellular metabolism, contributes to the renewal and restructuring of the dermis, facilitates the penetration of other active substances, has a direct and indirect positive effect on many biochemical processes of the skin, helps to maintain a more uniform skin color.

IDP- 5 (Oligopeptide-20 Nano-Encapsulated): Increase the thickness of the epidermis vital reduces and prevents the formation of fine lines and wrinkles, strengthens skin elasticity by inducing the synthesis of collagen and elastin, it contributes to the regeneration and reorganization of the constituents the MEC (Extra Cellular Matrix).

DIPEPTIDE- 4: Bio-protector broad range, protects the skin from oxidative stress, improves the natural defense mechanisms against oxidative stress (SOD and catalase), reduces carbonylation protein, improves the protection of the DNA, decreased lipid peroxidation, it protects against damage glycation.

SOLAR FILTERS: Medium protection against UVA-UVB.

Special cream suitable for delicate and sensitive skin, it facilitates renewal of the skin and structural skin barrier reinforcement. It contains a mix of substances that revitalize different metabolic mechanisms, combating the first signs of aging and reinforcing the skin barrier against external aggressions.

Prevents loss of skin tone and elasticity, making your skin smoother and helping you achieve a uniform skin tone The skin is better protected, hydrated and rebalanced with a skin barrier reinforced.

PHAs: Substances with multiple properties capable of acting on the bond strength of corneo- desmosomes preserving and restoring proper cellular metabolism of the corneocytes (Stratum Corneum). It has strong moisturizing properties, it counteracts oxygen free radicals, improves the barrier function, especially in sensitive skin, improves skin texture.

N.S.L.E. (Natural Skin Lipid Equivalent): Dermo-compatible formula which helps regenerate the lipid film and makes the skin more resistant to external aggressions.

OLIGOPEPTIDE+TETRAPEPTIDE-7: Matrikines able to activate certain genes involved in ECM (Extra Cellular Matrix) renewal mechanisms and cell proliferation. They activate neosynthesis of type I- IV collagen, fibronectin and GAGs.It Improves tone and elasticity.of the skin.

SOLAR FILTERS: Medium protection against UVA-UVB.